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The Polo kinase Cdc5 is regulated at multiple levels in the adaptation response to telomere dysfunction

Telomere dysfunction activates the DNA damage checkpoint to induce a cell cycle arrest. After an extended period of time, however, cells can bypass the arrest and undergo cell division despite the persistence of the initial damage, a process called adaptation to DNA damage. The Polo kinase Cdc5 in S...

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Detalles Bibliográficos
Autores principales: Coutelier, Héloïse, Ilioaia, Oana, Le Peillet, Jeanne, Hamon, Marion, D’Amours, Damien, Teixeira, Maria Teresa, Xu, Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836022/
https://www.ncbi.nlm.nih.gov/pubmed/36342193
http://dx.doi.org/10.1093/genetics/iyac171