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The Polo kinase Cdc5 is regulated at multiple levels in the adaptation response to telomere dysfunction
Telomere dysfunction activates the DNA damage checkpoint to induce a cell cycle arrest. After an extended period of time, however, cells can bypass the arrest and undergo cell division despite the persistence of the initial damage, a process called adaptation to DNA damage. The Polo kinase Cdc5 in S...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836022/ https://www.ncbi.nlm.nih.gov/pubmed/36342193 http://dx.doi.org/10.1093/genetics/iyac171 |