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A recombinant spike protein subunit vaccine confers protective immunity against SARS-CoV-2 infection and transmission in hamsters

Multiple safe and effective vaccines that elicit immune responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are necessary to respond to the ongoing coronavirus disease 2019 (COVID-19) pandemic. Here, we developed a protein subunit vaccine composed of spike ectodomain prote...

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Detalles Bibliográficos
Autores principales: Wu, Yangtao, Huang, Xiaofen, Yuan, Lunzhi, Wang, Shaojuan, Zhang, Yali, Xiong, Hualong, Chen, Rirong, Ma, Jian, Qi, Ruoyao, Nie, Meifeng, Xu, Jingjing, Zhang, Zhigang, Chen, Liqiang, Wei, Min, Zhou, Ming, Cai, Minping, Shi, Yang, Zhang, Liang, Yu, Huan, Hong, Junping, Wang, Zikang, Hong, Yunda, Yue, Mingxi, Li, Zonglin, Chen, Dabing, Zheng, Qingbing, Li, Shaowei, Chen, Yixin, Cheng, Tong, Zhang, Jun, Zhang, Tianying, Zhu, Huachen, Zhao, Qinjian, Yuan, Quan, Guan, Yi, Xia, Ningshao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836081/
https://www.ncbi.nlm.nih.gov/pubmed/34285130
http://dx.doi.org/10.1126/scitranslmed.abg1143