Cargando…
A recombinant spike protein subunit vaccine confers protective immunity against SARS-CoV-2 infection and transmission in hamsters
Multiple safe and effective vaccines that elicit immune responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are necessary to respond to the ongoing coronavirus disease 2019 (COVID-19) pandemic. Here, we developed a protein subunit vaccine composed of spike ectodomain prote...
Autores principales: | Wu, Yangtao, Huang, Xiaofen, Yuan, Lunzhi, Wang, Shaojuan, Zhang, Yali, Xiong, Hualong, Chen, Rirong, Ma, Jian, Qi, Ruoyao, Nie, Meifeng, Xu, Jingjing, Zhang, Zhigang, Chen, Liqiang, Wei, Min, Zhou, Ming, Cai, Minping, Shi, Yang, Zhang, Liang, Yu, Huan, Hong, Junping, Wang, Zikang, Hong, Yunda, Yue, Mingxi, Li, Zonglin, Chen, Dabing, Zheng, Qingbing, Li, Shaowei, Chen, Yixin, Cheng, Tong, Zhang, Jun, Zhang, Tianying, Zhu, Huachen, Zhao, Qinjian, Yuan, Quan, Guan, Yi, Xia, Ningshao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836081/ https://www.ncbi.nlm.nih.gov/pubmed/34285130 http://dx.doi.org/10.1126/scitranslmed.abg1143 |
Ejemplares similares
-
SARS-CoV-2 spike produced in insect cells elicits high neutralization titres
in non-human primates
por: Li, Tingting, et al.
Publicado: (2020) -
Lineage-mosaic and mutation-patched spike proteins for broad-spectrum COVID-19 vaccine
por: Wu, Yangtao, et al.
Publicado: (2022) -
A Bacterially Expressed SARS-CoV-2 Receptor Binding Domain Fused With Cross-Reacting Material 197 A-Domain Elicits High Level of Neutralizing Antibodies in Mice
por: Liu, Liqin, et al.
Publicado: (2022) -
Gender associates with both susceptibility to infection and pathogenesis of SARS-CoV-2 in Syrian hamster
por: Yuan, Lunzhi, et al.
Publicado: (2021) -
The neutralizing breadth of antibodies targeting diverse conserved epitopes between SARS-CoV and SARS-CoV-2
por: Xiong, Hualong, et al.
Publicado: (2022)