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Aggressive Afterload Lowering to Improve the Right Ventricle: A New Target for Medical Therapy in Pulmonary Arterial Hypertension?

Despite numerous therapeutic advances in pulmonary arterial hypertension, patients continue to suffer high morbidity and mortality, particularly considering a median age of 50 years. This article explores whether early, robust reduction of right ventricular afterload would facilitate substantial imp...

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Detalles Bibliográficos
Autores principales: Vizza, Carmine Dario, Lang, Irene M., Badagliacca, Roberto, Benza, Raymond L., Rosenkranz, Stephan, White, R. James, Adir, Yochai, Andreassen, Arne K., Balasubramanian, Vijay, Bartolome, Sonja, Blanco, Isabel, Bourge, Robert C., Carlsen, Jørn, Camacho, Rafael Enrique Conde, D’Alto, Michele, Farber, Harrison W., Frantz, Robert P., Ford, H. James, Ghio, Stefano, Gomberg-Maitland, Mardi, Humbert, Marc, Naeije, Robert, Orfanos, Stylianos E., Oudiz, Ronald J., Perrone, Sergio V., Shlobin, Oksana A., Simon, Marc A., Sitbon, Olivier, Torres, Fernando, Luc Vachiery, Jean, Wang, Kuo-Yang, Yacoub, Magdi H., Liu, Yan, Golden, Gil, Matsubara, Hiromi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836222/
https://www.ncbi.nlm.nih.gov/pubmed/34905704
http://dx.doi.org/10.1164/rccm.202109-2079PP