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New potential for an old kid on the block: Impact of premorbid metformin use on lactate kinetics, kidney injury and mortality in sepsis and septic shock, an observational study

INTRODUCTION: Sepsis and septic shock cause significant mortality worldwide, with no targeted molecular therapies available. Metformin has pleomorphic effects that may be beneficial in sepsis, but at present, the impact of metformin exposure on sepsis remains controversial. Metformin might alter lac...

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Detalles Bibliográficos
Autores principales: Van Moorter, Nina, Tackaert, Thomas, De Decker, Koen, Van Vlem, Bruno, De Neve, Nikolaas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836235/
https://www.ncbi.nlm.nih.gov/pubmed/36444165
http://dx.doi.org/10.1002/edm2.382