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Meiotic resetting of the cellular Sod1 pool is driven by protein aggregation, degradation, and transient LUTI-mediated repression

Gametogenesis requires packaging of the cellular components needed for the next generation. In budding yeast, this process includes degradation of many mitotically stable proteins, followed by their resynthesis. Here, we show that one such case—Superoxide dismutase 1 (Sod1), a protein that commonly...

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Detalles Bibliográficos
Autores principales: Vander Wende, Helen M., Gopi, Mounika, Onyundo, Megan, Medrano, Claudia, Adanlawo, Temiloluwa, Brar, Gloria Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836244/
https://www.ncbi.nlm.nih.gov/pubmed/36622328
http://dx.doi.org/10.1083/jcb.202206058