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Dynamic induction of the myelin‐associated growth inhibitor Nogo‐A in perilesional plasticity regions after human spinal cord injury

The myelin‐associated inhibitor Nogo‐A (Reticulon 4, RTN4) restricts axonal outgrowth, plasticity, and neural circuitry formation in experimental models of spinal cord injury (SCI) and is targeted in clinical interventions starting treatment within 4 weeks post‐SCI. Specifically, Nogo‐A expressed by...

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Detalles Bibliográficos
Autores principales: Schwaiger, Carmen, Haider, Thomas, Endmayr, Verena, Zrzavy, Tobias, Gruber, Victoria E., Ricken, Gerda, Simonovska, Anika, Hametner, Simon, Schwab, Jan M., Höftberger, Romana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836369/
https://www.ncbi.nlm.nih.gov/pubmed/35698271
http://dx.doi.org/10.1111/bpa.13098