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Attenuation of Piwil2 induced by hypoxic postconditioning prevents cerebral ischemic injury by inhibiting CREB2 promoter methylation

Epigenetic modification contributes to the pathogenesis of cerebral ischemia. Piwil2 belongs to the PIWI proteins subfamily and has a key role in the regulation of gene transcription through epigenetics. However, the roles of Piwil2 in cerebral ischemia have not been investigated. In this study, we...

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Detalles Bibliográficos
Autores principales: Zhan, Lixuan, Chen, Meiyan, Pang, Taoyan, Li, Xinyu, Long, Long, Liang, Donghai, Peng, Linhui, Sun, Weiwen, Xu, En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836370/
https://www.ncbi.nlm.nih.gov/pubmed/35794855
http://dx.doi.org/10.1111/bpa.13109