Targeting the interaction of GABA(B) receptors with CaMKII with an interfering peptide restores receptor expression after cerebral ischemia and inhibits progressive neuronal death in mouse brain cells and slices

Cerebral ischemia is the leading cause for long‐term disability and mortality in adults due to massive neuronal death. Currently, there is no pharmacological treatment available to limit progressive neuronal death after stroke. A major mechanism causing ischemia‐induced neuronal death is the excessi...

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Detalles Bibliográficos
Autores principales: Balakrishnan, Karthik, Hleihil, Mohammad, Bhat, Musadiq A., Ganley, Robert P., Vaas, Markus, Klohs, Jan, Zeilhofer, Hanns Ulrich, Benke, Dietmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836377/
https://www.ncbi.nlm.nih.gov/pubmed/35698024
http://dx.doi.org/10.1111/bpa.13099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836377/
https://www.ncbi.nlm.nih.gov/pubmed/35698024
http://dx.doi.org/10.1111/bpa.13099

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