Structures of RecBCD in complex with phage-encoded inhibitor proteins reveal distinctive strategies for evasion of a bacterial immunity hub

Following infection of bacterial cells, bacteriophage modulate double-stranded DNA break repair pathways to protect themselves from host immunity systems and prioritise their own recombinases. Here, we present biochemical and structural analysis of two phage proteins, gp5.9 and Abc2, which target th...

Descripción completa

Detalles Bibliográficos
Autores principales: Wilkinson, Martin, Wilkinson, Oliver J, Feyerherm, Connie, Fletcher, Emma E, Wigley, Dale B, Dillingham, Mark S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836394/
https://www.ncbi.nlm.nih.gov/pubmed/36533901
http://dx.doi.org/10.7554/eLife.83409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836394/
https://www.ncbi.nlm.nih.gov/pubmed/36533901
http://dx.doi.org/10.7554/eLife.83409

Ejemplares similares