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Excessive response to provocation rather than disinhibition mediates irritable behaviour in Huntington’s disease

BACKGROUND: Irritable and impulsive behaviour are common in Huntington’s disease (HD: an autosomal dominant disorder causing degeneration in cortico-striatal networks). However, the cognitive mechanisms underlying these symptoms remain unclear, and previous research has not determined if common mech...

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Detalles Bibliográficos
Autores principales: McLauchlan, Duncan James, Linden, David E. J., Rosser, Anne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836783/
https://www.ncbi.nlm.nih.gov/pubmed/36643017
http://dx.doi.org/10.3389/fnins.2022.993357