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Excessive response to provocation rather than disinhibition mediates irritable behaviour in Huntington’s disease
BACKGROUND: Irritable and impulsive behaviour are common in Huntington’s disease (HD: an autosomal dominant disorder causing degeneration in cortico-striatal networks). However, the cognitive mechanisms underlying these symptoms remain unclear, and previous research has not determined if common mech...
Autores principales: | McLauchlan, Duncan James, Linden, David E. J., Rosser, Anne E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836783/ https://www.ncbi.nlm.nih.gov/pubmed/36643017 http://dx.doi.org/10.3389/fnins.2022.993357 |
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