Phloretin inhibits glucose transport and reduces inflammation in human retinal pigment epithelial cells

During age-related macular degeneration (AMD), chronic inflammatory processes, possibly fueled by high glucose levels, cause a breakdown of the retinal pigment epithelium (RPE), leading to vision loss. Phloretin, a natural dihydroxychalcone found in apples, targets several anti-inflammatory signalin...

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Detalles Bibliográficos
Autores principales: Hytti, Maria, Ruuth, Johanna, Kanerva, Iiris, Bhattarai, Niina, Pedersen, Maria L., Nielsen, Carsten U., Kauppinen, Anu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836970/
https://www.ncbi.nlm.nih.gov/pubmed/35771396
http://dx.doi.org/10.1007/s11010-022-04504-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836970/
https://www.ncbi.nlm.nih.gov/pubmed/35771396
http://dx.doi.org/10.1007/s11010-022-04504-2

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