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Regulation of angiotensin-converting enzyme 2 isoforms by type 2 inflammation and viral infection in human airway epithelium

SARS-CoV-2 enters human cells through its main receptor, angiotensin-converting enzyme 2 (ACE2), which constitutes a limiting factor of infection. Recent findings demonstrating novel ACE2 isoforms implicate that this receptor is regulated in a more complex way than previously anticipated. However, i...

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Detalles Bibliográficos
Autores principales: Stocker, Nino, Radzikowska, Urszula, Wawrzyniak, Paulina, Tan, Ge, Huang, Mengting, Ding, Mei, Akdis, Cezmi A., Sokolowska, Milena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Inc. on behalf of Society for Mucosal Immunology. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836991/
https://www.ncbi.nlm.nih.gov/pubmed/36642382
http://dx.doi.org/10.1016/j.mucimm.2022.12.001