MiR92b-3p synthetic analogue impairs zebrafish embryonic development, leading to ocular defects, decreased movement and hatching rate, and increased mortality

The aim of this study was to examine the effect of microRNA 92b-3p (MiR92b-3p) overexpression on the embryonic development of zebrafish. A synthetic MiR92b-3p analogue (mirVana™ mimic, in vivo-ready) was injected at doses up to 5 ng/embryo into the yolk sac of embryos (2–16 cell stage). At 24 h post...

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Detalles Bibliográficos
Autores principales: Kranert, Kilian, Woźny, Maciej, Podlasz, Piotr, Wąsowicz, Krzysztof, Brzuzan, Paweł
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Animal Genetics • Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837005/
https://www.ncbi.nlm.nih.gov/pubmed/36274083
http://dx.doi.org/10.1007/s13353-022-00732-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837005/
https://www.ncbi.nlm.nih.gov/pubmed/36274083
http://dx.doi.org/10.1007/s13353-022-00732-w

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