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MiR92b-3p synthetic analogue impairs zebrafish embryonic development, leading to ocular defects, decreased movement and hatching rate, and increased mortality
The aim of this study was to examine the effect of microRNA 92b-3p (MiR92b-3p) overexpression on the embryonic development of zebrafish. A synthetic MiR92b-3p analogue (mirVana™ mimic, in vivo-ready) was injected at doses up to 5 ng/embryo into the yolk sac of embryos (2–16 cell stage). At 24 h post...
Autores principales: | Kranert, Kilian, Woźny, Maciej, Podlasz, Piotr, Wąsowicz, Krzysztof, Brzuzan, Paweł |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837005/ https://www.ncbi.nlm.nih.gov/pubmed/36274083 http://dx.doi.org/10.1007/s13353-022-00732-w |
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