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Tyrosine kinase SRC-induced YAP1-KLF5 module regulates cancer stemness and metastasis in triple-negative breast cancer

SRC is the first identified oncogene, and its aberrant activation has been implicated as a driving event in tumor initiation and progression. However, its role in cancer stemness regulation and the underlying regulatory mechanism are still elusive. Here, we identified a YAP1 tyrosine phosphorylation...

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Detalles Bibliográficos
Autores principales: Zou, Hailin, Luo, Juan, Guo, Yibo, Tong, Tongyu, Liu, Yuchen, Chen, Yun, Xiao, Yunjun, Ye, Liping, Zhu, Chengming, Deng, Liang, Wang, Bo, Pan, Yihang, Li, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837006/
https://www.ncbi.nlm.nih.gov/pubmed/36633714
http://dx.doi.org/10.1007/s00018-023-04688-w