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In silico and in vitro analysis of the impact of single substitutions within EXO-motifs on Hsa-MiR-1246 intercellular transfer in breast cancer cell

MiR-1246 has recently gained much attention and many studies have shown its oncogenic role in colorectal, breast, lung, and ovarian cancers. However, miR-1246 processing, stability, and mechanisms directing miR-1246 into neighbor cells remain still unclear. In this study, we aimed to determine the r...

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Detalles Bibliográficos
Autores principales: Rybarczyk, Agnieszka, Lehmann, Tomasz, Iwańczyk-Skalska, Ewa, Juzwa, Wojciech, Pławski, Andrzej, Kopciuch, Kamil, Blazewicz, Jacek, Jagodziński, Paweł P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837009/
https://www.ncbi.nlm.nih.gov/pubmed/36394782
http://dx.doi.org/10.1007/s13353-022-00730-y