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Linagliptin treatment is associated with altered cobalamin (VitB12) homeostasis in mice and humans

Linagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor used for the treatment of type 2 diabetes, with additional beneficial effects for the kidney. Treatment of mice with linagliptin revealed increased storage of cobalamin (Cbl, Vitamin B12) in organs if a standard Cbl diet (30 µg Cbl/kg chow) i...

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Detalles Bibliográficos
Autores principales: Tammen, Harald, Kömhoff, Martin, Delić, Denis, Lund, Søren S., Hocher, Berthold, Frankenreiter, Sandra, Hess, Rüdiger, von Eynatten, Maximilian, Mark, Michael, Klein, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837112/
https://www.ncbi.nlm.nih.gov/pubmed/36635409
http://dx.doi.org/10.1038/s41598-023-27648-7