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Linagliptin treatment is associated with altered cobalamin (VitB12) homeostasis in mice and humans
Linagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor used for the treatment of type 2 diabetes, with additional beneficial effects for the kidney. Treatment of mice with linagliptin revealed increased storage of cobalamin (Cbl, Vitamin B12) in organs if a standard Cbl diet (30 µg Cbl/kg chow) i...
Autores principales: | Tammen, Harald, Kömhoff, Martin, Delić, Denis, Lund, Søren S., Hocher, Berthold, Frankenreiter, Sandra, Hess, Rüdiger, von Eynatten, Maximilian, Mark, Michael, Klein, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837112/ https://www.ncbi.nlm.nih.gov/pubmed/36635409 http://dx.doi.org/10.1038/s41598-023-27648-7 |
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