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Machine learning enabled subgroup analysis with real-world data to inform clinical trial eligibility criteria design

Overly restrictive eligibility criteria for clinical trials may limit the generalizability of the trial results to their target real-world patient populations. We developed a novel machine learning approach using large collections of real-world data (RWD) to better inform clinical trial eligibility...

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Detalles Bibliográficos
Autores principales: Xu, Jie, Zhang, Hao, Zhang, Hansi, Bian, Jiang, Wang, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837131/
https://www.ncbi.nlm.nih.gov/pubmed/36635438
http://dx.doi.org/10.1038/s41598-023-27856-1