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Cortical inhibitory but not excitatory synaptic transmission and circuit refinement are altered after the deletion of NMDA receptors during early development

Neurons in the cerebral cortex form excitatory and inhibitory circuits with specific laminar locations. The mechanisms underlying the development of these spatially specific circuits is not fully understood. To test if postsynaptic N-methyl-D-aspartate (NMDA) receptors on excitatory neurons are requ...

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Detalles Bibliográficos
Autores principales: Deng, Rongkang, Chang, Minzi, Kao, Joseph P. Y., Kanold, Patrick O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837136/
https://www.ncbi.nlm.nih.gov/pubmed/36635357
http://dx.doi.org/10.1038/s41598-023-27536-0