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Genetic complementation fosters evolvability in complex fitness landscapes

The ability of natural selection to optimize traits depends on the topology of the genotype-fitness map (fitness landscape). Epistatic interactions produce rugged fitness landscapes, where adaptation is constrained by the presence of low-fitness intermediates. Here, we used simulations to explore ho...

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Detalles Bibliográficos
Autores principales: Segredo-Otero, Ernesto, Sanjuán, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837146/
https://www.ncbi.nlm.nih.gov/pubmed/36635310
http://dx.doi.org/10.1038/s41598-022-26588-y