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Genetic complementation fosters evolvability in complex fitness landscapes
The ability of natural selection to optimize traits depends on the topology of the genotype-fitness map (fitness landscape). Epistatic interactions produce rugged fitness landscapes, where adaptation is constrained by the presence of low-fitness intermediates. Here, we used simulations to explore ho...
Autores principales: | Segredo-Otero, Ernesto, Sanjuán, Rafael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837146/ https://www.ncbi.nlm.nih.gov/pubmed/36635310 http://dx.doi.org/10.1038/s41598-022-26588-y |
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