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Tubular aryl hydratocarbon receptor upregulates EZH2 to promote cellular senescence in cisplatin-induced acute kidney injury

Acute kidney injury (AKI) is one of the serious clinical syndromes with high morbidity and mortality. Despite substantial progress in understanding the mechanism of AKI, no effective drug is available for treatment or prevention. In this study, we identified that a ligand-activated transcription fac...

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Detalles Bibliográficos
Autores principales: Wen, Li, Ren, Qian, Guo, Fan, Du, Xiaoyan, Yang, Hongliu, Fu, Ping, Ma, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837170/
https://www.ncbi.nlm.nih.gov/pubmed/36635272
http://dx.doi.org/10.1038/s41419-022-05492-3