TIMP-1 is a novel ligand of Amyloid Precursor Protein and triggers a proinflammatory phenotype in human monocytes

The emerging cytokine tissue inhibitor of metalloproteinases-1 (TIMP-1) correlates with the progression of inflammatory diseases, including cancer. However, the effects of TIMP-1 on immune cell activation and underlying molecular mechanisms are largely unknown. Unbiased ligand-receptor-capture-scree...

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Detalles Bibliográficos
Autores principales: Eckfeld, Celina, Schoeps, Benjamin, Häußler, Daniel, Frädrich, Julian, Bayerl, Felix, Böttcher, Jan Philipp, Knolle, Percy, Heisz, Simone, Prokopchuk, Olga, Hauner, Hans, Munkhbaatar, Enkhtsetseg, Demir, Ihsan Ekin, Hermann, Chris D., Krüger, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837626/
https://www.ncbi.nlm.nih.gov/pubmed/36629908
http://dx.doi.org/10.1083/jcb.202206095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837626/
https://www.ncbi.nlm.nih.gov/pubmed/36629908
http://dx.doi.org/10.1083/jcb.202206095

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