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Downregulated miR-181a alleviates H(2)O(2)-induced oxidative stress and cellular senescence by targeting PDIA6 in human foreskin fibroblasts()

BACKGROUND: Oxidative stress is strongly associated with cellular senescence. Numerous studies have indicated that microRNAs (miRNAs) play a critical part in cellular senescence. MiR-181a was reported to induce cellular senescence, however, the potential mechanism of miR-181a in hydrogen peroxide (H...

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Detalles Bibliográficos
Autores principales: Huang, Yan, Yan, Huimin, Yang, Yanqing, Zhou, Jinfei, Xu, Qijun, Meng, Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837654/
https://www.ncbi.nlm.nih.gov/pubmed/36244946
http://dx.doi.org/10.1016/j.abd.2021.12.007