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Effectiveness of Secondary Risk–Reducing Strategies in Patients With Unilateral Breast Cancer With Pathogenic Variants of BRCA1 and BRCA2 Subjected to Breast-Conserving Surgery: Evidence-Based Simulation Study

BACKGROUND: Approximately 62% of patients with breast cancer with a pathogenic variant (BRCA1 or BRCA2) undergo primary breast-conserving therapy. OBJECTIVE: The study aims to develop a personalized risk management decision support tool for carriers of a pathogenic variant (BRCA1 or BRCA2) who under...

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Detalles Bibliográficos
Autores principales: Maksimenko, Jelena, Rodrigues, Pedro Pereira, Nakazawa-Miklaševiča, Miki, Pinto, David, Miklaševičs, Edvins, Trofimovičs, Genadijs, Gardovskis, Jānis, Cardoso, Fatima, Cardoso, Maria João
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JMIR Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837710/
https://www.ncbi.nlm.nih.gov/pubmed/36580360
http://dx.doi.org/10.2196/37144