The Parkinson’s disease variant rs356182 regulates neuronal differentiation independently from alpha-synuclein

One of the most significant risk variants for Parkinson’s disease (PD), rs356182, is located at the PD-associated locus near the alpha-synuclein (α-syn) encoding gene, SNCA. SNCA-proximal variants, including rs356182, are thought to function in PD risk through enhancers via allele-specific regulator...

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Detalles Bibliográficos
Autores principales: Prahl, Jordan D, Pierce, Steven E, van der Schans, Edwin J C, Coetzee, Gerhard A, Tyson, Trevor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837835/
https://www.ncbi.nlm.nih.gov/pubmed/35866299
http://dx.doi.org/10.1093/hmg/ddac161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837835/
https://www.ncbi.nlm.nih.gov/pubmed/35866299
http://dx.doi.org/10.1093/hmg/ddac161

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