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CD4(+) and CD8(+) regulatory T cell characterization in the rat using a unique transgenic Foxp3-EGFP model

BACKGROUND: Regulatory T cells (Treg) in diverse species include CD4(+) and CD8(+) T cells. In all species, CD8(+) Treg have been only partially characterized and there is no rat model in which CD4(+) and CD8(+) FOXP3(+) Treg are genetically tagged. RESULTS: We generated a Foxp3-EGFP rat transgenic...

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Detalles Bibliográficos
Autores principales: Ménoret, Séverine, Tesson, Laurent, Remy, Séverine, Gourain, Victor, Sérazin, Céline, Usal, Claire, Guiffes, Aude, Chenouard, Vanessa, Ouisse, Laure-Hélène, Gantier, Malika, Heslan, Jean-Marie, Fourgeux, Cynthia, Poschmann, Jeremie, Guillonneau, Carole, Anegon, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837914/
https://www.ncbi.nlm.nih.gov/pubmed/36635667
http://dx.doi.org/10.1186/s12915-022-01502-0