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Knockdown of SEMA7A alleviates MPP(+)‐induced apoptosis and inflammation in BV2 microglia via PPAR‐γ activation and MAPK inactivation

INTRODUCTION: The inflammation mediated by microglial cells plays an important role in the process of neurodegenerative diseases. Recent evidence indicates that semaphorin 7A (SEMA7A) is implicated in various neurodegenerative diseases, but whether it plays a role in Parkinson's disease (PD) re...

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Detalles Bibliográficos
Autores principales: Qi, Weinan, Zeng, Dan, Xiong, Xiaoshuan, Hu, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837934/
https://www.ncbi.nlm.nih.gov/pubmed/36705403
http://dx.doi.org/10.1002/iid3.756