Blocking interleukin-23 ameliorates neuromuscular and thymic defects in myasthenia gravis

Acetylcholine receptor (AChR) myasthenia gravis (MG) is a chronic autoimmune disease characterized by muscle weakness. The AChR(+) autoantibodies are produced by B-cells located in thymic ectopic germinal centers (eGC). No therapeutic approach is curative. The inflammatory IL-23/Th17 pathway is acti...

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Detalles Bibliográficos
Autores principales: Villegas, José A., Van Wassenhove, Jérôme, Merrheim, Judith, Matta, Karen, Hamadache, Samy, Flaugère, Clémence, Pothin, Pauline, Truffault, Frédérique, Hascoët, Sébastien, Santelmo, Nicola, Alifano, Marco, Berrih-Aknin, Sonia, le Panse, Rozen, Dragin, Nadine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837970/
https://www.ncbi.nlm.nih.gov/pubmed/36639663
http://dx.doi.org/10.1186/s12974-023-02691-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837970/
https://www.ncbi.nlm.nih.gov/pubmed/36639663
http://dx.doi.org/10.1186/s12974-023-02691-3

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