Reporter gene assays and chromatin-level assays define substantially non-overlapping sets of enhancer sequences

BACKGROUND: Transcriptional enhancers are essential for gene regulation, but how these regulatory elements are best defined remains a significant unresolved question. Traditional definitions rely on activity-based criteria such as reporter gene assays, while more recently, biochemical assays based o...

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Detalles Bibliográficos
Autores principales: Lindhorst, Daniel, Halfon, Marc S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837977/
https://www.ncbi.nlm.nih.gov/pubmed/36639739
http://dx.doi.org/10.1186/s12864-023-09123-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837977/
https://www.ncbi.nlm.nih.gov/pubmed/36639739
http://dx.doi.org/10.1186/s12864-023-09123-9

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