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Reporter gene assays and chromatin-level assays define substantially non-overlapping sets of enhancer sequences
BACKGROUND: Transcriptional enhancers are essential for gene regulation, but how these regulatory elements are best defined remains a significant unresolved question. Traditional definitions rely on activity-based criteria such as reporter gene assays, while more recently, biochemical assays based o...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837977/ https://www.ncbi.nlm.nih.gov/pubmed/36639739 http://dx.doi.org/10.1186/s12864-023-09123-9 |