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Arginase-1 inhibition reduces migration ability and metastatic colonization of colon cancer cells

BACKGROUND: Arginase-1 (ARG1), a urea cycle-related enzyme, catalyzes the hydrolysis of arginine to urea and ornithine, which regulates the proliferation, differentiation, and function of various cells. However, it is unclear whether ARG1 controls the progression and malignant alterations of colon c...

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Detalles Bibliográficos
Autores principales: Wang, Xiangdong, Xiang, Huihui, Toyoshima, Yujiro, Shen, Weidong, Shichi, Shunsuke, Nakamoto, Hiroki, Kimura, Saori, Sugiyama, Ko, Homma, Shigenori, Miyagi, Yohei, Taketomi, Akinobu, Kitamura, Hidemitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838026/
https://www.ncbi.nlm.nih.gov/pubmed/36639644
http://dx.doi.org/10.1186/s40170-022-00301-z