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Arginase-1 inhibition reduces migration ability and metastatic colonization of colon cancer cells
BACKGROUND: Arginase-1 (ARG1), a urea cycle-related enzyme, catalyzes the hydrolysis of arginine to urea and ornithine, which regulates the proliferation, differentiation, and function of various cells. However, it is unclear whether ARG1 controls the progression and malignant alterations of colon c...
Autores principales: | Wang, Xiangdong, Xiang, Huihui, Toyoshima, Yujiro, Shen, Weidong, Shichi, Shunsuke, Nakamoto, Hiroki, Kimura, Saori, Sugiyama, Ko, Homma, Shigenori, Miyagi, Yohei, Taketomi, Akinobu, Kitamura, Hidemitsu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838026/ https://www.ncbi.nlm.nih.gov/pubmed/36639644 http://dx.doi.org/10.1186/s40170-022-00301-z |
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