Efficient biosynthesis of (R)-mandelic acid from styrene oxide by an adaptive evolutionary Gluconobacter oxydans STA

BACKGROUND: (R)-mandelic acid (R-MA) is a highly valuable hydroxyl acid in the pharmaceutical industry. However, biosynthesis of optically pure R-MA remains significant challenges, including the lack of suitable catalysts and high toxicity to host strains. Adaptive laboratory evolution (ALE) was a p...

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Detalles Bibliográficos
Autores principales: Liu, Fei, Zhou, Junping, Hu, Mengkai, Chen, Yan, Han, Jin, Pan, Xuewei, You, Jiajia, Xu, Meijuan, Yang, Taowei, Shao, Minglong, Zhang, Xian, Rao, Zhiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838050/
https://www.ncbi.nlm.nih.gov/pubmed/36639820
http://dx.doi.org/10.1186/s13068-023-02258-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838050/
https://www.ncbi.nlm.nih.gov/pubmed/36639820
http://dx.doi.org/10.1186/s13068-023-02258-7

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