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Inhibition of histone deacetylase 6 destabilizes ERK phosphorylation and suppresses cancer proliferation via modulation of the tubulin acetylation-GRP78 interaction

BACKGROUND: The leading cause of cancer-related mortality worldwide is lung cancer, and its clinical outcome and prognosis are still unsatisfactory. The understanding of potential molecular targets is necessary for clinical implications in precision diagnostic and/or therapeutic purposes. Histone de...

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Detalles Bibliográficos
Autores principales: Wattanathamsan, Onsurang, Chantaravisoot, Naphat, Wongkongkathep, Piriya, Kungsukool, Sakkarin, Chetprayoon, Paninee, Chanvorachote, Pithi, Vinayanuwattikun, Chanida, Pongrakhananon, Varisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838051/
https://www.ncbi.nlm.nih.gov/pubmed/36639650
http://dx.doi.org/10.1186/s12929-023-00898-3