Alamandine/MrgD axis prevents TGF-β1-mediated fibroblast activation via regulation of aerobic glycolysis and mitophagy

BACKGROUND: Idiopathic pulmonary fibrosis is a chronic progressive, lethal disease in which ectopic lung fibroblast (LF) activation plays a vital part. We have previously shown that alamandine (ALA) exerts anti-fibrosis effects via the MAS-related G-protein coupled receptor D (MrgD). Here, we furthe...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Zhang, Yue, Huang, Wenhui, Yuan, Yafei, Hong, Qiaohui, Xie, Zhanzhan, Li, Lijuan, Chen, Yixin, Li, Xu, Meng, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838062/
https://www.ncbi.nlm.nih.gov/pubmed/36635651
http://dx.doi.org/10.1186/s12967-022-03837-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838062/
https://www.ncbi.nlm.nih.gov/pubmed/36635651
http://dx.doi.org/10.1186/s12967-022-03837-2

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