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Tumor suppressor genes are reactivated by miR-26A1 via enhancer reprogramming in NSCLC

Non-small cell lung cancer (NSCLC) is one of the most malignant epithelial tumors. Studies have suggested that DNA hypermethylation of promoters and abnormal histone modifications could induce tumor suppressor genes (TSGs) downregulation in NSCLC. However, the exact mechanism of TSGs downregulation...

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Detalles Bibliográficos
Autores principales: Li, Hongling, Da, Dezhuan, Yu, Wenqiang, Chen, Lu, Yang, Shuai, Zhang, Baolong, Wang, Yongying, Li, Linyu, Dang, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838096/
https://www.ncbi.nlm.nih.gov/pubmed/35921230
http://dx.doi.org/10.1093/hmg/ddac185