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Cell-based therapeutic strategies for treatment of spinocerebellar ataxias: an update

Spinocerebellar ataxias are heritable neurodegenerative diseases caused by a cytosine-adenine-guanine expansion, which encodes a long glutamine tract (polyglutamine) in the respective wild-type protein causing misfolding and protein aggregation. Clinical features of polyglutamine spinocerebellar ata...

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Detalles Bibliográficos
Autores principales: Correia, Joana Sofia, Duarte-Silva, Sara, Salgado, António José, Maciel, Patrícia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838137/
https://www.ncbi.nlm.nih.gov/pubmed/36453395
http://dx.doi.org/10.4103/1673-5374.355981