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Do tau-synaptic long-term depression interactions in the hippocampus play a pivotal role in the progression of Alzheimer’s disease?

Cognitive decline in Alzheimer’s disease correlates with the extent of tau pathology, in particular tau hyperphosphorylation that initially appears in the transentorhinal and related regions of the brain including the hippocampus. Recent evidence indicates that tau hyperphosphorylation caused by eit...

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Detalles Bibliográficos
Autores principales: Hu, Zhengtao, Ondrejcak, Tomas, Yu, Pengpeng, Zhang, Yangyang, Yang, Yin, Klyubin, Igor, Kennelly, Sean P., Rowan, Michael J., Hu, Neng-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838152/
https://www.ncbi.nlm.nih.gov/pubmed/36453396
http://dx.doi.org/10.4103/1673-5374.360166