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UHPLC-ESI-QE-Orbitrap-MS based metabolomics reveals the antioxidant mechanism of icaritin on mice with cerebral ischemic reperfusion

BACKGROUND: Icaritin (ICT) has been previously demonstrated to display protective effects against cerebral ischemic reperfusion (I/R) by inhibiting oxidative stress, but the mechanism remains unclear. This study aimed to explore the mechanism from the perspective of metabolomics. METHODS: A mice cer...

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Detalles Bibliográficos
Autores principales: Tang, Yunfeng, Sun, Lixin, Zhao, Yun, Yao, Jingchun, Feng, Zhong, Liu, Zhong, Zhang, Guimin, Sun, Chenghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838208/
https://www.ncbi.nlm.nih.gov/pubmed/36643627
http://dx.doi.org/10.7717/peerj.14483