Structure of SALL4 zinc finger domain reveals link between AT-rich DNA binding and Okihiro syndrome

Spalt-like 4 (SALL4) maintains vertebrate embryonic stem cell identity and is required for the development of multiple organs, including limbs. Mutations in SALL4 are associated with Okihiro syndrome, and SALL4 is also a known target of thalidomide. SALL4 protein has a distinct preference for AT-ric...

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Detalles Bibliográficos
Autores principales: Watson, James A, Pantier, Raphaël, Jayachandran, Uma, Chhatbar, Kashyap, Alexander-Howden, Beatrice, Kruusvee, Valdeko, Prendecki, Michal, Bird, Adrian, Cook, Atlanta G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838217/
https://www.ncbi.nlm.nih.gov/pubmed/36635047
http://dx.doi.org/10.26508/lsa.202201588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838217/
https://www.ncbi.nlm.nih.gov/pubmed/36635047
http://dx.doi.org/10.26508/lsa.202201588

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