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Structure of SALL4 zinc finger domain reveals link between AT-rich DNA binding and Okihiro syndrome
Spalt-like 4 (SALL4) maintains vertebrate embryonic stem cell identity and is required for the development of multiple organs, including limbs. Mutations in SALL4 are associated with Okihiro syndrome, and SALL4 is also a known target of thalidomide. SALL4 protein has a distinct preference for AT-ric...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Life Science Alliance LLC
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838217/ https://www.ncbi.nlm.nih.gov/pubmed/36635047 http://dx.doi.org/10.26508/lsa.202201588 |