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In silico investigation of falcipain-2 inhibition by hybrid benzimidazole-thiosemicarbazone antiplasmodial agents: A molecular docking, molecular dynamics simulation, and kinetics study

The emergence of artemisinin-resistant variants of Plasmodium falciparum necessitates the urgent search for novel antimalarial drugs. In this regard, an in silico study to screen antimalarial drug candidates from a series of benzimidazole-thiosemicarbazone hybrid molecules with interesting antiplasm...

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Detalles Bibliográficos
Autores principales:	Nkungli, Nyiang Kennet, Fouegue, Aymard Didier Tamafo, Tasheh, Stanley Numbonui, Bine, Fritzgerald Kogge, Hassan, Abrar Ul, Ghogomu, Julius Numbonui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838286/ https://www.ncbi.nlm.nih.gov/pubmed/36622482 http://dx.doi.org/10.1007/s11030-022-10594-3

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