Discovery and biosynthesis of karnamicins as angiotensin converting enzyme inhibitors

Angiotensin-converting enzyme inhibitors are widely used for treatment of hypertension and related diseases. Here, six karnamicins E(1)-E(6) (1–6), which bear fully substituted hydroxypyridine and thiazole moieties are characterized from the rare actinobacterium Lechevalieria rhizosphaerae NEAU-A2....

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Detalles Bibliográficos
Autores principales: Yu, Zhiyin, Huang, Jian-Ping, Yang, Jing, Liu, Chongxi, Yan, Yijun, Wang, Li, Zhao, Junwei, Chen, Yin, Xiang, Wensheng, Huang, Sheng-Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838390/
https://www.ncbi.nlm.nih.gov/pubmed/36639377
http://dx.doi.org/10.1038/s41467-023-35829-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838390/
https://www.ncbi.nlm.nih.gov/pubmed/36639377
http://dx.doi.org/10.1038/s41467-023-35829-1

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