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Enhancing the protection of influenza virus vaccines with BECC TLR4 adjuvant in aged mice

Influenza A virus (IAV) is a leading cause of respiratory disease worldwide often resulting in severe morbidity and mortality. We have previously shown that the Bacterial Enzymatic Combinatorial Chemistry (BECC) adjuvants, BECC438 and BECC470, formulated with an influenza virus hemagglutinin (HA) pr...

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Detalles Bibliográficos
Autores principales: Haupt, Robert, Baracco, Lauren, Harberts, Erin M., Loganathan, Madhumathi, Kerstetter, Lucas J., Krammer, Florian, Coughlan, Lynda, Ernst, Robert K., Frieman, Matthew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838488/
https://www.ncbi.nlm.nih.gov/pubmed/36639569
http://dx.doi.org/10.1038/s41598-023-27965-x