Biomechanical activation of blood platelets via adhesion to von Willebrand factor studied with mesoscopic simulations

Platelet adhesion and activation are essential initial processes of arterial and microvascular hemostasis, where high hydrodynamic forces from the bloodflow impede coagulation. The process relies on von Willebrand factor (VWF)—a linear multimeric protein of blood plasma plays a pivotal role in mecha...

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Detalles Bibliográficos
Autores principales: Belyaev, Aleksey V., Kushchenko, Yulia K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838538/
https://www.ncbi.nlm.nih.gov/pubmed/36627458
http://dx.doi.org/10.1007/s10237-022-01681-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838538/
https://www.ncbi.nlm.nih.gov/pubmed/36627458
http://dx.doi.org/10.1007/s10237-022-01681-3

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