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pH Dependence of Succinimide-Ester-Based Protein Cross-Linking for Structural Mass Spectrometry Applications

[Image: see text] Within the research field of cross-linking mass spectrometry (XL-MS), the most commonly used cross-linking reagents are succinimide-ester-based (e.g., disuccinimidyl suberate (DSS)). These reagents primarily cross-link lysine side chains. So far, they have predominantly been used t...

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Detalles Bibliográficos
Autores principales: Trabjerg, Esben, Keller, Arend, Leitner, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838815/
https://www.ncbi.nlm.nih.gov/pubmed/36785722
http://dx.doi.org/10.1021/acsmeasuresciau.1c00032